TABLE OF CONTENTS
CHAPTER ONE
1.0 INTRODUCTION
CHAPTER TWO
LITERATURE REVIEW
2.0. SENA TORA
2.1.1 TAXONOMY OF SENNA TORA [NATURE SERVE, 2007]
2.1.2 GEOGRAPHICAL DISTRIBUTION OF SENNA TORA
2.1.3 GROWTH REQUIREMENTS OF SENNA TORA
2.1.4 PROPAGATION OF SENNA TORA
2.1.5 IMPORTANCE USESOF SENNA TORA
2.2. LIVER
2.2.1 ANATOMY OF THE LIVER
2.2.2 STRUCTURE OF THE LIVER
2.2.3 FUNCTIONS OF THE LIVER
2.2.4 HEPATIC METABOLISM
2.2.5 CHOLESTEROL SYNTHESIS
2.2.6 PATHWAY FOR THE SYNTHESIS OF CHOLESTEROL
2.2.7 LIVER DAMAGE INTOXICATION
2.2.8 CAUSES OF LIVER DAMAGE
2.2.9 LIVER DISEASES
2.2.10 TOXICITY
2.2.11 TISSUE LESSION
2.2.12 HEPATOTOXICITY
2.3 HEPATOTOXICITY OF CARBON TETRACHLORIDE
2.3.1 BIOTRANSFORMATION OF CARBON TETRACHLORIDE
2.3.2 ACTION OF CARBON TETRACHLORIDE [CCL4]
2.3.4 PROPERTIES OF CCL4
2.3.5 HAZARDOUS EFFECTS OF CCL4
2.3.6 USES OF CARBON TETRACHLORIDE
2.3.7 BIOTRANSFORMATION AND COVALENT BINDING
2.4 LIVER ENZYMES AND FUNCTIONS
2.5 OXIDATIVE STRESS AND RADICAL REACTIONS
2.6 LIPID PEROXIDATION AND FREE RADICALS
2.7 REVERSING LIVER DAMAGE
2.8 REGULATIONS OF CHOLESTEROL LEVELS
CHAPTER THREE
MATERIALS AND METHODS
3.0 MATERIALS
3.1 PLANT MATERIALS
3.2 ANIMALS
3.3 EQUIPMENTS
3.4 CHEMICALS AND REAGENTS
3.5 EXPERIMENTAL DESIGN
3.6 METHODS
3.6.1 PREPARATION OF PLANT MATERIALS
3.6.2 EXTRACTION OF PLANT MATERIAL
3.7 ASSAY OF CHOLESTEROL PRINCIPLE
3.8 REAGENT COMPOSITION
3.9 ASSAY PROCEDURE
CHAPTER FOUR
RESULTS
4.0 EFFECT OF CARBON TETRACHLORIDE AND SENNA TORA EXTRACT ON CHOLESTEROL LEVEL
CHAPTER FIVE
5.0 DISCUSSION AND CONCLUSION
5.1 SUGGESTION FOR FURTHER RESEARCH
REFERENCES
APPENDIX
